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ラットがレバーを押し続ける行動にニコチンが及ぼす影響と衝動性について
https://doi.org/10.34360/00005193
https://doi.org/10.34360/0000519382fda4bd-04e2-4803-9635-4fcbdfdb5db8
名前 / ファイル | ライセンス | アクション |
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011_20 (612.8 kB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2011-05-25 | |||||
タイトル | ||||||
タイトル | ラットがレバーを押し続ける行動にニコチンが及ぼす影響と衝動性について | |||||
言語 | ||||||
言語 | jpn | |||||
キーワード | ||||||
主題 | Naoya, Murota, Hisatsugu, Miyata, Kosuke, Sawa, nicotine, impulsive behavior, lever-holding task | |||||
資源タイプ | ||||||
資源タイプ | departmental bulletin paper | |||||
ID登録 | ||||||
ID登録 | 10.34360/00005193 | |||||
ID登録タイプ | JaLC | |||||
別言語のタイトル(英) | ||||||
タイトル | The effect of nicotine on lever-holding response in rats | |||||
作成者 |
室田, 尚哉
× 室田, 尚哉× 宮田, 久嗣× 澤, 幸祐 |
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内容記述 | ||||||
内容記述 | Impulsivity, the tendency to act without foresight, is a characteristic of behavior that can being seen in everyday life, but high level of impulsivity is associated with a number of psychiatric disorders including attention deficit hyperactivity disorder (ADHD) and drug addiction. It has been suggested that impulsivity is not a unitary construct, but rather a multi-faceted construct. This study take up the behavioral paradigm that rats were required to keep pressing a lever to assess these impulsive behavior. In this paradigm, rats were required to keep pressing a lever for 4 seconds to obtain electrical stimulation of medial forebrain bundle, and to release the lever to begin next trial once they obtained electrical stimulation. Nicotine (0.4mg/kg, s.c.), suggested to increase impulsivity, had no effect on the percentage of responses to keep pressing the lever for 4 seconds, but decreased response latencies, and accelerated to release the lever after they had obtained a electrical stimulation. These results suggested that nicotine decreased impulsive behavior, specially to stop responses occur. | |||||
公開者 | ||||||
出版者 | 専修大学人間科学学会 | |||||
ISSN | ||||||
収録物識別子 | 2185-8276 | |||||
書誌レコードID | ||||||
収録物識別子 | AA12515444 | |||||
書誌情報 |
専修人間科学論集. 心理学篇 巻 1, p. 71-79, 発行日 2011-03-15 |
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出版タイプ | ||||||
出版タイプ | NA |